Syncytiotrophoblast Is a Barrier to Maternal-Fetal Transmission of Herpes Simplex Virus1
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چکیده
منابع مشابه
Fetal ventriculomegaly and herpes encephalitis following primary maternal herpes simplex infection.
Uteroplacental transmission of a primary herpes simplex virus (HSV) infection in pregnancy has been reported; however, HSV ventriculomegaly of the neonate has not been well documented in utero. We present a case of a 19-year-old woman who developed a primary HSV outbreak at 17 weeks of gestation and was treated with acyclovir. A congenital malformation scan at 18 weeks of gestation demonstrated...
متن کاملMaternal intrauterine herpes simplex virus infection leading to persistent fetal vasculature.
Herpes simplex virus can cause serious ocular and systemic disease in the neonate. The mode of transmission to the neonate is usually from the maternal birth canal to the fetus intrapartum; but much more rarely, hematogenous transplacental infection can affect the developing fetus months prior to birth. Persistent fetal vasculature occurs when there is persistence of the fetal ocular vasculatur...
متن کاملMaternal and neonatal herpes simplex virus infections.
Genital herpes infections are extremely common worldwide and ~22% of pregnant women are infected with herpes simplex virus. Eighty percent of those affected with genital herpes are unaware of being infected. The most devastating consequence of maternal genital herpes is neonatal herpes disease. Fortunately, neonatal herpes simplex infections are uncommon but due to the morbidity and mortality a...
متن کاملPlacental Syncytiotrophoblast Constitutes a Major Barrier to Vertical Transmission of Listeria monocytogenes
Listeria monocytogenes is an important cause of maternal-fetal infections and serves as a model organism to study these important but poorly understood events. L. monocytogenes can infect non-phagocytic cells by two means: direct invasion and cell-to-cell spread. The relative contribution of each method to placental infection is controversial, as is the anatomical site of invasion. Here, we rep...
متن کاملValacyclovir to reduce transmission of genital herpes simplex virus infection.
fallacy. Am J Epidemiol 1988; 127:893–904. 3. Greenland S, Robins J. Invited commentary: ecologic studies–biases, misconceptions, and counterexamples. Am J Epidemiol 1994; 139: 747–60. 4. Blaser MJ, Chen Y, Reibman J. Does Helicobacter pylori protect against asthma and allergy? Gut 2008; 57:561–7. 5. Höök-Nikanne J, Pérez-Pérez GI, Blaser MJ. Antigenic characterization of Helicobacter pylori st...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2002
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.102.004325